Agent for the treatment of chronic prostatitis
Androprost Plus
- Acute and chronic bacterial prostatitis
- Infectious and inflammatory diseases caused by microorganisms sensitive to lomefloxacin
- Conditions before and after surgical intervention on the prostate gland
Medicine
Properties and indications
- 01
Acute and chronic bacterial prostatitis
- 02
Infectious and inflammatory diseases caused by microorganisms sensitive to lomefloxacin
- 03
Conditions before and after surgical intervention on the prostate gland
Brief description
10 rectal suppositories
Lomefloxacin, prostate extract
Pharmacological properties
Pharmacotherapeutic group:
Antimicrobial agent, fluoroquinolone
Pharmacological action:
The combined preparation Androprost Plus has antimicrobial and anti-inflammatory properties. Lomefloxacin is a broad-spectrum bactericidal agent from the fluoroquinolone group. It acts on the bacterial enzyme DNA gyrase, which provides supercoiling, forms a complex with its tetramer (gyrase subunits A2B2) and disrupts DNA transcription and replication, leading to the death of the microbial cell.
Highly active against gram-negative aerobic microorganisms:
Neisseria gonorrhoeae, Neisseria meningitides, Escherichia coli, Citrobacter diversus, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Salmonella spp., Shigella spp., Moraxella morganii, Haemophilus influenzae e parainfluenzae, Legionella pneumophila, Pseudomonas aeruginosa.
Moderately sensitive to the preparation are Staphylococcus aureus, Staphylococcus Epidermidis, Serratia liquifaciens, Serratia marcescens, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Chlamydia trachomatis, Hafnia alvei, Citrobacter freundii, Aeromonas hydrophila, Proteus mirabilis, Proteus stuartii, Providencia rettgeri, Providencia alcalifaciens, Klebsiella oxytoca, Klebsiella ozaenae, Enterobacter aerogenes, Enterobacter agglomerans.
Resistant to the preparation are Streptococcus spp., Pseudomonas cepacia, Ureaplasma urealyticum, Treponema pallidum, Mycoplasma hominis and anaerobic bacteria.
It acts on most microorganisms at low concentrations (the concentration required to inhibit the growth of 90% of strains is usually no more than 1 mcg/ml). Resistance develops rarely. Prostate extract has an organotropic action on the prostate. It reduces the degree of edema and leukocyte infiltration of the prostate gland, normalizes the secretory function of the epithelial cells, increases the number of lecithin granules in the acinar secretion, and stimulates the muscle tone of the urinary bladder. It reduces thrombus formation, has antiplatelet activity, and prevents the development of venular thrombosis in the prostate gland. It normalizes the parameters of the prostate and ejaculate. It reduces pain and discomfort and improves copulative function.
Contraindications
Hypersensitivity to the components of the preparation
Age under 18 years (period of skeletal formation and growth)
With caution: Cerebral atherosclerosis, epilepsy and other diseases of the central nervous system with epileptic syndrome
How to use
Rectally, 1 suppository once a day after an enema or spontaneous bowel movement.
Before use, the suppository should be removed from the blister pack.
After administration of Androprost Plus, it is advisable to remain in bed for 30-40 minutes.
The course of treatment continues until the pathogen disappears from the prostate secretion and lasts from 10 to 30 days (the duration of treatment is determined by the physician individually for each patient).
Composition
Each suppository contains:
- Active ingredients: prostate extract – 100 mg (equivalent to 20 mg of water-soluble peptides), lomefloxacin hydrochloride – 400 mg
- Excipients: suppository base – hard fat (Witepsol) – sufficient quantity to obtain a suppository weighing 2.0 g.
Side effects
The side effects of Androprost Plus, with the exception of allergic reactions, are associated with the presence of the antibiotic lomefloxacin in its composition.
Allergic reactions:
Skin itching, urticaria, photosensitivity, erythema multiforme exudativum (Stevens-Johnson syndrome).
Nervous system:
Asthenia, dizziness, nervousness, anxiety, fatigue, malaise, headache.
Effect on the ability to drive vehicles and operate machinery:
During treatment, caution should be exercised when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Additional information
Dosage form:
Rectal suppositories 400 mg + 20 mg.
5 suppositories in a blister pack; two blister packs together with the instructions for use are placed in a cardboard box.
Shelf life:
2 years. Do not use the preparation after the expiration date.
Storage conditions:
Store in a dry place, protected from light, at a temperature not exceeding 25°C.
Keep out of the reach of children.
Catalogue
